Project 1

Human EPSCs for genomic medicine of immune disorders and for drug discovery

Team

Professor Chak Sing Lau

HKU
Leader

Professor Pengtao Liu

HKU
Co-Pls & Collaborators

Dr. Bo Gao

HKU
Co-Pls & Collaborators

Project Summary

Working with genome and stem cell initiatives in Cambridge and Hong Kong, CTSCB will establish projects to link genotype to phenotype through genetically-defined stem cell-based models of immune disease. Our data demonstrate that human EPSCs reprogrammed from somatic cells have considerably reduced variations among the lines of the same or different individuals.